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KMID : 0370220040480060364
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Yakhak Hoeji
2004 Volume.48 No. 6 p.364 ~ p.368
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The Prevalence of Macrolide Antibiotics Resistance in the Clinical Isolates of Common Respiratory Pathogens
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윤은정/Yoon EJ
하장범/최응칠/심미자/Ha JB/Choi EC/Shim MJ
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Abstract
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The prevalence of resistance to a range of macrolides was determined for clinical isolates of common respiratory pathogens using NCCLS testing methods and interpretative criteria.71.4% of Streptococcus pneumoniae, 62.3% of Staphylococcus aureus, 50.8% of coagulase-negative staphylococci and 4.4% of Strpetococcus pyogenes were erythromycin resistant. Also, the rates of resistance to other macrolides and clindamycin in these clinical isolates were as high as to eryth -romycin. Almost all of the macrolide-resistant isolates were positive for erm of the methylase gene, or mef of the efflux gene.
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